MonetDB has been designed to use the available resources without many tuning knobs. Functional enhancements are collected in autoloading scripts, which are executed when a database is created.
Other resources are mostly gathered upon need from the operating system environment. MonetDB aims to use as much of the main memory available, as many cores as can be practically deployed in parallel processing of queries, and trying to avoid going to a slow disk. As such, it is a rather aggressive system, which find immediate competition with ongoing heavy demand applications, e.g. a browser with a ton of open windows.
We recommend to use MonetDB in production settings on a dedicated server or a sizeable Cloud server.